“Can science prove or disprove God?” sounds like one question. In practice, people mean very different things by “God,” “proof,” and even “science.” A claim about a particular event in the natural world can invite observation. A claim about an ultimate reason for existence may be philosophical. Treating both as the same kind of claim makes a serious conversation harder than it needs to be.
Suppose someone says a specific event happened at a specific time and left physical traces. Researchers can examine records, objects, or measurements and ask whether the predicted traces are present. They can compare other explanations. If the evidence is weak, a particular account may become less credible. That finding would concern the event and its proposed explanation; it would not, by itself, settle every possible belief about God. Likewise, a surprising observation does not automatically identify a divine cause.
Now consider a different claim: that the universe depends on a source beyond it, or that existence has an ultimate purpose. Philosophers have argued for and against such ideas for centuries. The Stanford Encyclopedia of Philosophy describes several versions of cosmological arguments, each with premises about causation, contingency, or a beginning. Cosmology can inform discussion of those premises. But a measured age or expansion history does not complete a philosophical argument about why anything exists. Other premises still need defending.
This boundary is not a declaration that science and religion never meet. Religious traditions sometimes make claims about nature, history, or human life that can be compared with evidence. Believers also differ in whether a scientific finding challenges, deepens, or has little bearing on their faith. Philosophers disagree about how far empirical methods can reach. The useful move is to ask for the exact claim rather than announce one verdict for every version of belief.
“What would we expect to observe if this were true?” is a good scientific question when the claim offers a testable expectation. “Does this explanation follow from those facts?” is a good philosophical question even when no telescope can answer it alone. Both questions require care. Neither requires dismissing a person who arrives with a different conviction or pretending that every answer is equally supported.
We may leave the conversation without a final answer. That is not wasted effort. We can learn which part of our view rests on a measurement, which part on an argument, and which part on faith or experience. Once those parts are visible, disagreement becomes more honest, and curiosity has room to work.